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TLR3 Polyclonal Antibody

Polyclonal Antibody to detect TLR3 in Human, Mouse, Rat samples
Catalog #: 3445
SKU-Size Size Price Qty
3445-100 100 µg
$285.00
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Product Details

Antibody Target TLR3
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Recombinant human TLR3
Accession # O15455
Gene ID 7098
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 l antigen affinity purified rabbit anti-human TLR3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol and 0.02% thimerosal.
Purification Affinity purified rabbit IgG
Species Reactivity Human
Application Western blot
Application & Usage Western blot: 1-4 µg
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds)RNA, induces the activation of NF-kB, through MyD88-dependent and –independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.


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