Anti-TLR10 antibody (ab53631)
Key features and details
- Goat polyclonal to TLR10
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TLR10 antibody
See all TLR10 primary antibodies -
Description
Goat polyclonal to TLR10 -
Host species
Goat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Cow -
Immunogen
Synthetic peptide: C HNRIQQLDLK TFEFNKELRY LDLSNNRLKS V, corresponding to amino acids 80-111 of Human TLR10
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.1% Sodium azide
Constituents: 0.1% BSA, 0.21% Potassium phosphate, 0.812% Sodium chloride, PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab53631 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/250.
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Notes |
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IHC-P
1/250. |
Target
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Function
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. -
Tissue specificity
Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines. -
Sequence similarities
Belongs to the Toll-like receptor family.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 539791 Cow
- Entrez Gene: 81793 Human
- Omim: 606270 Human
- SwissProt: Q6GV17 Cow
- SwissProt: Q9BXR5 Human
- Unigene: 120551 Human
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Alternative names
- CD 290 antibody
- CD 290 antigen antibody
- CD290 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab53631 has been referenced in 2 publications.
- Latorre E et al. Listeria monocytogenes Inhibits Serotonin Transporter in Human Intestinal Caco-2 Cells. Microb Ecol 72:730-9 (2016). PubMed: 27488594
- Chougule P et al. Isolation and characterization of human primary enterocytes from small intestine using a novel method. Scand J Gastroenterol 47:1334-43 (2012). Flow Cyt ; Human . PubMed: 22943429