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Tigecycline

A protein translocation inhibitor
Catalog #: 1956
SKU-Size Size Price Qty
1956-5 5 mg
$80.00
1956-25 25 mg
$285.00
More Sizes Get Quote

Product Details

Alternate Name N-[(5aR,6aS,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5,5a,6,6a,7,8,9,10,10a,11-decahydrotetracen-2-yl]-2-(tert-butylamino)acetamide
Appearance Off-white to yellow brown solid
CAS # 220620-09-7
Molecular Formula C₂₉H₃₉N₅O₈
Molecular Weight 586.65
Purity ≥98% by HPLC
Solubility DMSO (~ 3 mg/ml with warming)
SMILES CC(C)(C)NCC(=O)NC1=C(C2=C(CC3CC4C(C(=O)C(=C(C4(C(=O)C3=C2O)O)O)C(=O)N)N(C)C)C(=C1)N(C)C)O
InChi InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36-37,40,42H,8-9,11H2,1-7H3,(H2,30,41)(H,32,35)/t12-,14-,21-,29-/m0/s1
InChi Key SOVUOXKZCCAWOJ-HJYUBDRYSA-N
PubChem CID 54686904
MDL Number MFCD00935753
Handling Protect from light and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A glycylglycine type of antibiotic derived from tetracycline. Inhibits protein translation in bacteria by binding to the 30S ribosomal subunit and blocking entry of amino-acyl tRNA molecules into the A site of the ribosome. This prevents incorporation of amino acid residues into elongating peptide chains.


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