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Thioredoxin Reductase 1 (TXNRD1) Antibody

Polyclonal Antibody to detect Thioredoxin Reductase 1 (TXNRD1) in Human, Mouse, Rat samples
Catalog #: 7005
SKU-Size Size Price Qty
7005-30T 30 µg
$89.00
7005-100 100 µg
$265.00
More Sizes Get Quote

Product Details

Antibody Target Thioredoxin Reductase 1 (TXNRD1)
Alternate Name Thioredoxin Reductase, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR
Host Rabbit
Antibody Type Polyclonal
Isotype rabbit IgG
Immunogen Synthetic peptide of human TXNRD1 from the middle region
Accession # Q16881
Gene ID 7296
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.
Purification Affinity purified rabbit IgG
Species Reactivity Human, Mouse, Rat
Application Western blot
Positive Control Western blot:human serum,3T3 cell lysate, mouse muscle, rat kidney, rat liver
Application & Usage Western blot: 1-4 µg
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Thioredoxin reductase 1 is an enzyme that in humans is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.


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