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Thiocolchicine

A tubulin polymerization and microtubule assembly inhibitor
Catalog #: 2213

In stock

SKU-Size Size Price Qty
2213-5 5 mg
$80.00
2213-25 25 mg
$265.00
More Sizes Get Quote

Product Details

Alternate Name 10-Demethoxy-10-methylthiocolchicine; NSC 186301
Appearance Yellow solid
CAS # 2730-71-4
Molecular Formula C₂₂H₂₅NO₅S
Molecular Weight 415.5
Purity ³95% by NMR
Solubility DMSO
SMILES CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)OC
InChi InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
InChi Key CMEGANPVAXDBPL-UHFFFAOYSA-N
PubChem CID 546854
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

An antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor and axonal cytoskeleton modulator; apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors.


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