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TGX-155

An inhibitor of PI3K
Catalog #: B2917
SKU-Size Size Price Qty
B2917-1 1 mg
$65.00
B2917-5 5 mg
$255.00
More Sizes Get Quote

Product Details

Alternate Name 8-(4-Fluoro-2-methylphenoxy)-2-(4-morpholinyl)-4(1H)-quinolinone
Appearance Solid
CAS # 351071-90-4
Molecular Formula C₂₀H₁₉FN₂O₃
Molecular Weight 354.37
Purity 95%
Solubility Soluble in DMSO in 0
SMILES CC1=C(C=CC(=C1)F)OC2=CC=CC3=C2NC(=CC3=O)N4CCOCC4
InChi InChI=1S/C20H19FN2O3/c1-13-11-14(21)5-6-17(13)26-18-4-2-3-15-16(24)12-19(22-20(15)18)23-7-9-25-10-8-23/h2-6,11-12H,7-10H2,1H3,(H,22,24)
InChi Key FZTZVNFKDPBYKA-UHFFFAOYSA-N
PubChem CID 16757579
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

TGX-155 is an inhibitor of phosphoinositide 3-kinase (PI3K). PI3Ks and their lipid product phosphatidylinositol-3,4,5-trisphosphate are involved in signaling events in many cellular processes. TGX-155 selectively inhibits the p110β catalytic subunit of Class I PI3K with an IC₅₀ of 30 nM in vitro.


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