TGF-beta1, human recombinant

A protein that controls proliferation, cellular differentiation, & other functions in most cells
Catalog #: 4342 | abID: ab285556

Product Details

abID ab285556
Alternate Name Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor
Gene Symbol TGFB1
Gene ID 7040
Accession # P01137
Source CHO cells
Appearance Lyophilized protein
Physical Form Description Lyophilized from Sodium Citrate, pH3.5 buffer
Molecular Weight 25.0 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The ED₅₀ as determined by the ability of TGF-β1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is <0.05 ng/ml, corresponding to a specific activity of >2 x 10⁷ units/mg.
Reconstitution Instructions Reconstitution in H₂O to a concentration of 50 ug/ml (e.g., 5 ug/100 μl) will yield a solution of 1 mM citrate buffer (pH 3.5). The solution can then be stored at 4°C for 1 month. It is recommended that further dilutions be made in PBS containing 2 mg/ml
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


TGF-β1 (Transforming Growth Factor-β1) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-β1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

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