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TGF-beta Receptor II Antibody

Catalog #: 5639R
SKU-Size Size Price Qty
5639R-30T 30 µg
$89.00
5639R-100 100 µg
$245.00
More Sizes Get Quote

Product Details

Antibody Target TGF-b Receptor II
Alternate Name Transforming growth factor-beta receptor type II, Transforming growth factor-beta receptor type 2, TGF-beta type II receptor, TbetaR-II; TGFR-2, TGFG2, TGFR 2
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 555 of rat TGF-β Receptor II.
Accession # NP_112394
Gene ID 81810
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot and Immunohistochemistry (5 µg/ml)
Application & Usage The antibody can be used for Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 5639RBP-50) is available separately.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

TGF-β (Transforming growth factor-beta superfamily members are critical regulators of cell proliferation, differentiation, morphogenesis, and pathogenesis. TGF-beta receptor is a serine/threonine kinase receptor complex that consists of two distinct transmembrane proteins known as type I and type II receptors. In response to ligand binding, the type II receptors form a stable complex with the type I receptors allowing phosphorylation and thus activation of the type I receptor kinases.


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