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TGF-β3, Mouse Recombinant

Plays an important role in wound repair/scarring, osteoblast proliferation, chemotaxis, and collagen synthesis
Catalog #: 7588
SKU-Size Size Price Qty
7588-5 5 μg
$375.00
7588-50 50 μg
$2,255.00
7588-500 500 μg
$10,850.00
More Sizes Get Quote

Product Details

Alternate Name Transforming growth factor beta-3
Gene Symbol TGF-beta-3
Gene ID 21809
Accession # P17125
Source E. coli
Appearance Liquid
Physical Form Description 0.25 mg/mL solution containing 20% ethanol and 0.12% acetic acid (AcOH)
Molecular Weight 25.5 kDa.
Purity by SDS-PAGE ≥98%
Endotoxin Level Measured by kinetic LAL analysis and is typically ≤ 1 EU/μg protein
Biological Activity The activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically less than 0.05 ng/mL.
Amino Acid Sequence ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
Handling Centrifuge the vial prior to opening.
Storage Conditions 4°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans

Details

The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-β isoforms (TGF-β1, -β2 and –β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-β3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis. Recombinant mouse TGF-β3 is a non-glycosylated, disulfide-linked homodimer, containing two 112 amino acid chains, with a total molecular weight of 25.5 kDa.


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