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Product Details
| Alternate Name | Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, LAP, TGFB1. |
|---|---|
| Gene Symbol | TGFB1 |
| Gene ID | 7040 |
| Accession # | P01137 |
| Source | E. coli |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized without any additives. |
| Molecular Weight | 15.09 kDa (279 to 390 aa + NT-His Tag). |
| Purity by SDS-PAGE | ≥95% |
| Reconstitution Instructions | Centrifuge the vial prior to opening. Reconstitute in water to a stock concentration of 1 mg/ml and further dilute in buffer of choice. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not to be used in humans |
Details
Transforming growth factor-betas (TGF-βs) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF-Beta 1, TGF-Beta 2 and TGF-Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-beta 1 is involved in hematopoiesis and endothelial differentiation.
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