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A potent JAK2 inhibitor
Catalog #: 2314
SKU-Size Size Price Qty
2314-1 1 mg
2314-5 5 mg
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Product Details

Alternate Name N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide; SAR302503
Appearance White solid
CAS # 936091-26-8
Molecular Formula C₂₇H₃₆N₆O₃S
Molecular Weight 524.68
Purity ≥98% by HPLC
Solubility DMSO (~100 mg/ml) or Ethanol (~ 20 mg/ml)
InChi InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)
PubChem CID 16722836
MDL Number MFCD09038564
Handling Protect from air and light
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


TG101348 is a potent, and selective inhibitor of JAK2 (IC₅₀ = 3 nM). It has a 35- and 334-fold selectivity over JAK3 and JAK1, respectively.

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