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A potent, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (Clk)
Catalog #: 1905
SKU-Size Size Price Qty
1905-5 5 mg
1905-25 25 mg
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Product Details

Alternate Name (Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one
Appearance Pale yellow solid
CAS # 300801-52-9
Molecular Formula C₁₃H₁₅NO₂S
Molecular Weight 249.33
Purity ≥98% by TLC
Solubility DMSO (>30 mg/ml)
InChi InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3
PubChem CID 647991
MDL Number MFCD00624584
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (Clk) (Ki = 10 nM for mClk1/Sty; IC₅₀ = 20 nM, 200 nM, >10 µM, and 15 nM for mClk1, mClk2, mClk3, and mClk4, respectively). Recently, it has been shown that TG003 promotes the skipping of exon 31 in the endogenous dystrophin gene in a dose-dependent manner and increases the production of the dystrophin protein.

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