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A potent JAK2 inhibitor
Catalog #: B3220
SKU-Size Size Price Qty
B3220-5 5 mg
B3220-25 25 mg
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Product Details

Alternate Name N-tert-butyl-3-(5-methyl-2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide
Peptide Sequence N/A
Appearance White to off-white solid
CAS # 936091-14-4
Molecular Formula C₂₆H₃₅N₇O₂S
Molecular Weight 509.67
Purity ≥98% by HPLC
Solubility >10 mg/ml DMSO
InChi InChI=1S/C26H35N7O2S/c1-19-18-27-25(29-20-9-11-22(12-10-20)33-15-13-32(5)14-16-33)30-24(19)28-21-7-6-8-23(17-21)36(34,35)31-26(2,3)4/h6-12,17-18,31H,13-16H2,1-5H3,(H2,27,28,29,30)
PubChem CID 16722832
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


TG101209 is a potent and selective inhibitor of Janus Kinase 2 (JAK2) (IC50 = 6 nM). It displays 28-fold selectivity over JAK3 (IC50 = 169 nM). TG101209 induces dose- and time-dependent cytotoxicity in a variety of multiple myeloma (MM) cell lines.

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