TFEB Antibody

Master regulator of metabolism and immune response
Catalog #: A2307 | abID:

Product Details

Antibody Target Human TFEB
Alternate Name Transcription factor EB; Class E basic helix-loop-helix Protein 35; BHLHE35; TCFEB; T-Cell Transcription Factor EB; ALPHATFEB
Host Rabbit
Antibody Type Polyclonal
Isotype IgG
Immunogen Recombinant human TFEB protein
Accession # P19484
Gene ID 7942
Appearance Liquid
Formulation In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification Affinity purification
Species Reactivity Human, Mouse, Rat
Application Western Blotting, Immunofluorescence (IF), Immunohistochemistry (IHC)
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

The T cell transcription factor EB (TFEB) acts as a master regulator of lysosomal biogenesis, autophagy, lysosomal exocytosis, lipid catabolism, energy metabolism, and immune response. In association with TFE3, TFEB activates the expression of CD40L in T cells, thus playing a role in T cell-dependent antibody responses. TFEB is involved in the immune response to infection by Staphylococcus bacteria, possibly by the regulation of cytokine and chemokine expression.


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