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A topoisomerase II inhibitor

WARNING: This product can expose you to chemicals including Teniposide, which is [are] known to the State of California to cause birth defects or other reproductive harm.  For more information go to
Catalog #: B2655
SKU-Size Size Price Qty
B2655-10 10 mg
B2655-50 50 mg
More Sizes Get Quote

Product Details

Alternate Name NSC 122819; VM-26; (5R,5aR,8aR,9S)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[[4,6-O-[(R)-2-thienylmethylene]-β-D-glucopyranosyl]oxy]-furo[3’,4’:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
Appearance White to off-white solid
CAS # 29767-20-2
Molecular Formula C₃₂H₃₂O₁₃S
Molecular Weight 656.65
Purity ≥98%
Solubility ~5 mg/ml DMSO
InChi InChI=1S/C32H32O13S/c1-37-19-6-13(7-20(38-2)25(19)33)23-14-8-17-18(42-12-41-17)9-15(14)28(16-10-39-30(36)24(16)23)44-32-27(35)26(34)29-21(43-32)11-40-31(45-29)22-4-3-5-46-22/h3-9,16,21,23-24,26-29,31-35H,10-12H2,1-2H3/t16-,21+,23+,24-,26+,27+,28+,29+,31+,32-/m0/s1
PubChem CID 452548
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Teniposide is a podophyllotoxin derivative that acts as a topoisomerase II inhibitor. Its cytostatic effects are related to its ability to stabilize the DNA-topoisomerase II complex during DNA replication, inducing DNA damage and cellular apoptosis. Teniposide has been widely used in the treatment of various cancers including, small cell lung cancer, malignant lymphoma, breast cancer, oral squamous cell carcinoma, and acute lymphoblastic leukemia.

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