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Temsirolimus (CCI-779, Torisel)

A mTOR inhibitor
Catalog #: 1600
SKU-Size Size Price Qty
1600-5 5 mg
$280.00
1600-25 25 mg
$835.00
More Sizes Get Quote

Product Details

Alternate Name CCI-779,Torisel
Appearance White to off-white solid
CAS # 162635-04-3
Molecular Formula C₅₆H₈₇NO₁₆
Molecular Weight 1030.29
Purity ≥99%
Solubility DMSO (200 mg/ml)
SMILES CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)OC(=O)C(C)(CO)CO)C)C)O)OC)C)C)C)OC
InChi InChI=1S/C56H87NO16/c1-33-17-13-12-14-18-34(2)45(68-9)29-41-22-20-39(7)56(67,73-41)51(63)52(64)57-24-16-15-19-42(57)53(65)71-46(30-43(60)35(3)26-38(6)49(62)50(70-11)48(61)37(5)25-33)36(4)27-40-21-23-44(47(28-40)69-10)72-54(66)55(8,31-58)32-59/h12-14,17-18,26,33,35-37,39-42,44-47,49-50,58-59,62,67H,15-16,19-25,27-32H2,1-11H3/b14-12+,17-13+,34-18+,38-26+/t33-,35-,36-,37-,39-,40+,41+,42+,44-,45+,46+,47-,49-,50+,56-/m1/s1
InChi Key CBPNZQVSJQDFBE-FUXHJELOSA-N
PubChem CID 6918289
MDL Number MFCD00934421
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

mTOR inhibitor with anti-cancer activity. It has anti-angiogenic effects which may contribute to the antitumor activity of temsirolimus observed in breast cancer. Temsirolimus shows synergistic in vivo anti-myeloma effects in combination with dexamethasone in a xenograft model.


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