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A potent, ATP-competitive FLT3 receptor tyrosine kinase inhibitor
Catalog #: B2212

In stock

SKU-Size Size Price Qty
B2212-5 5 mg
B2212-25 25 mg
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Product Details

Alternate Name 2-(3,4-dimethoxybenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
Appearance White solid
CAS # 301305-73-7
Molecular Formula C₁₈H₂₀N₂O₄S
Molecular Weight 360.43
Purity ≥98% by HPLC
Solubility DMSO (>10 mg/ml)
InChi InChI=1S/C18H20N2O4S/c1-23-12-8-7-10(9-13(12)24-2)17(22)20-18-15(16(19)21)11-5-3-4-6-14(11)25-18/h7-9H,3-6H2,1-2H3,(H2,19,21)(H,20,22)
PubChem CID 1048845
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


TCS-359 is a potent, ATP-competitive inhibitor of FLT3 receptor tyrosine kinase (IC₅₀ = 42 nM) that displays selectivity over a range of other kinases. It blocks the proliferation of myelomonocytic leukemia MV4-11 cells. TCS-359 synergistically increases the cytotoxicity of an AF4-mimetic peptide against MV4-11 cells.

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