Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

TC-E 5002

An inhibitor of KDM2/7
Catalog #: B2856
SKU-Size Size Price Qty
B2856-1 1 mg
$65.00
B2856-5 5 mg
$225.00
More Sizes Get Quote

Product Details

Alternate Name 3-[9-cyclopropylnonanoyl(hydroxy)amino]propanoic acid; N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-beta-alanine; 3-(9-cyclopropyl-N-hydroxynonanamido)propanoic acid
Appearance A crystalline solid
CAS # 1453071-47-0
Molecular Formula C₁₅H₂₇NO₄
Molecular Weight 285.38
Purity ≥98%
Solubility ~30 mg/ml in DMSO
~50 mg/ml in Ethanol
~10 mg/ml in DMF
~0.25 mg/ml in PBS, pH 7.2
SMILES C1CC1CCCCCCCCC(=O)N(CCC(=O)O)O
InChi InChI=1S/C15H27NO4/c17-14(16(20)12-11-15(18)19)8-6-4-2-1-3-5-7-13-9-10-13/h13,20H,1-12H2,(H,18,19)
InChi Key NEHSERYKENINRH-UHFFFAOYSA-N
PubChem CID 71735843
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

TC-E 5002 is an inhibitor of the histone lysine demethylase (KDM) subfamily KDM2/7. It potently inhibits KDM2A, KDM7A and KDM7B with an IC₅₀ of 6.8 μM, 0.2 μM and 1.2 μM respectively. It inhibits the growth of KYSE150 and HeLa cells with GI₅₀ values of 16 µM and 40 µM respectively and arrests cells in the G0/G1 phase of the cell cycle. It inhibits demethylation of H3K27me2 at similar concentrations.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.