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TC-E 5003

A selective protein arginine methyltransferase 1 (PRMT1) inhibitor
Catalog #: B1177
SKU-Size Size Price Qty
B1177-10 10 mg
B1177-50 50 mg
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Product Details

Alternate Name N,N'-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide
Appearance Off-white solid
CAS # 17328-16-4
Molecular Formula C₁₆H₁₄Cl₂N₂O₄S
Molecular Weight 401.26
Purity ≥98% by HPLC
Solubility DMSO (~20 mg/ml)
InChi InChI=1S/C16H14Cl2N2O4S/c17-9-15(21)19-11-1-5-13(6-2-11)25(23,24)14-7-3-12(4-8-14)20-16(22)10-18/h1-8H,9-10H2,(H,19,21)(H,20,22)
PubChem CID 87052
MDL Number MFCD00028183
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


TC-E 5003 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC₅₀ = 1.5 μM); displays no inhibitory activity against CARM1 and Set7/9 methyltransferases. Inhibits growth of MCF7a breast cancer cells and LNCaP prostate cancer cells.

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