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Takinib

A potent and selective TAK1 inhibitor
Catalog #: B2324

In stock

SKU-Size Size Price Qty
B2324-5 5 mg
$115.00
B2324-25 25 mg
$425.00
More Sizes Get Quote

Product Details

Alternate Name 3-N-(1-Propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide
Appearance Crystalline solid
CAS # 1111556-37-6
Molecular Formula C₁₈H₁₈N₄O₂
Molecular Weight 322.36
Purity ≥98% by HPLC
Solubility >25 mg/ml in DMSO
SMILES CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N
InChi InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
InChi Key UOZVVPXKJGOFIG-UHFFFAOYSA-N
PubChem CID 37750349
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Takinib is a potent and selective TAK1 inhibitor (IC₅₀ = 9.5 nM). Sensitizes cells to TNF-α-induced cell death, with potential implications for cancer and autoimmune diseases.


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