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TAF1 polyclonal antibody

Polyclonal Antibody to detect TAF1 in human samples.
Catalog #: 6845

In stock

$185.00

Product Details

Cat # +Size 6845-50
Size 50 μl
Antibody Target TAF1
Alternate Name TAF (II) 250, TBP-associated factor 250 kDa, p250, BA2R, CCG1, CCGS, TAF2A
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Polyclonal antibody raised in rabbit against human TAF1 (TATA box binding protein (TBP)-associated factor; Transcription initiation factor TFIID subunit 1), using the recombinant double bromodomain module of the protein.
Accession # P21675
Gene ID 6872
Appearance Colorless liquid
Formulation In PBS with 0.05% (W/V) sodium azide.
Purification Whole Anti-Sera
Species Reactivity Human.
Application Western blot
Positive Control Western blot: HeLa cells
Application & Usage Western Blot: 1:1000.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

TAF1 is the largest component and core scaffold of the TFIID basal transcription factor complex which also includes TBP. The protein is able to auto phosphorylate or trans phosphorylate other transcription factors such as TP53 on ‘Thr-55’, leading to MDM2-mediated degradation of TP53, and GTF2A1 and GTF2F1 on Ser residues. TAF1 possesses DNA-binding activity and is essential for progression of the G1 phase of the cell cycle.


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