Product Details
| Cat # +Size | 3682-100 |
|---|---|
| Size | 100 µg |
| Antibody Target | TAB 1 |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant full length protein of human TAB1 |
| Accession # | Q15750 |
| Gene ID | 10454 |
| Appearance | Colorless liquid |
| Formulation | Purified rabbit polyclonal antibody in 0.42% Potassium phosphate; 0.87% Sodium chloride, pH 7.3, 30% glycerol and 0.01% sodium azide. |
| Purification | Affinity purified |
| Species Reactivity | Human, mouse, rat |
| Application | WB |
| Positive Control | WB: MCF7; A431; Hela; mouse kidney; mouse heart whole cell lysates |
| Application & Usage | WB 1:500-1:2000 |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
TAB1 (TAK1 binding protein 1) is an adaptor protein that can activate TAK1 in vivo throμgh phosphorylation of TAK1, a mitogen-activated protein kinase kinase kinase. Once activated TAK1 phosphorylates MAPK kinase MKK4 and MKK3/6, which activate p38 MAPK and JNK, respectively.
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