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T0070907

A potent and selective antagonist of the human PPARγ
Catalog #: 2095
$120.00

Product Details

Cat # +Size 2095-5
Size 5 mg
Alternate Name 2-​Chloro-​5-​nitro-​N-​4-​pyridinyl-​benzamide
Appearance White solid
CAS # 313516-66-4
Molecular Formula C₁₂H₈ClN₃O₃
Molecular Weight 277.66
Purity ≥98% by HPLC
Solubility DMSO (100 mM) or Ethanol (100 mM)
SMILES C1=CC(=C(C=C1[N+](=O)[O-])C(=O)NC2=CC=NC=C2)Cl
InChi InChI=1S/C12H8ClN3O3/c13-11-2-1-9(16(18)19)7-10(11)12(17)15-8-3-5-14-6-4-8/h1-7H,(H,14,15,17)
InChi Key FRPJSHKMZHWJBE-UHFFFAOYSA-Nv
PubChem CID 2777391
MDL Number MFCD00121849
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

T0070907 is a potent and selective antagonist of the human PPARγ (IC50 = 1 nM). T0070907 suppresses breast cancer cell proliferation and motility via both PPARγ-dependent and –independent mechanisms.


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