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T-705 (Favipiravir)

An antiviral drug
Catalog #: 2778
SKU-Size Size Price Qty
2778-5 5 mg
$135.00
2778-25 25 mg
$510.00
More Sizes Get Quote

Product Details

Alternate Name 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide; Avigan
Appearance Light yellow to yellow solid
CAS # 259793-96-9
Molecular Formula C₅H₄FN₃O₂
Molecular Weight 157.1
Purity ≥98%
Solubility DMSO (>15 mg/ml)
SMILES C1=C(N=C(C(=O)N1)C(=O)N)F
InChi InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11)
InChi Key ZCGNOVWYSGBHAU-UHFFFAOYSA-N
PubChem CID 492405
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

T-705 (Favipiravir) is an antiviral drug that selectively inhibits the RNA-dependent RNA polymerase of influenza virus. It is phosphoribosylated by cellular enzymes to its active form, favipiravir-ribofuranosyl-5'-triphosphate (RTP). Favipiravir is active against a broad range of influenza viruses, including A(H1N1)pdm09, A(H5N1) and the recently emerged A(H7N9) avian virus. It also inhibits influenza strains resistant to current antiviral drugs, and shows a synergistic effect in combination with oseltamivir, thereby expanding influenza treatment options. Recently, T-705 has been shown to give 100% protection against aerosol Ebola virus E718 infection in immune-deficient mice as well as inhibiting Ebola virus infection in cell culture. . It has been shown to inhibit SARS-CoV-2 in vitro.


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