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Swi6 Antibody

Polyclonal Antibody to detect Swi6 in human, mouse and rat samples
Catalog #: 6285
SKU-Size Size Price Qty
6285-30T 30 µg
$89.00
6285-100 100 µg
$195.00
More Sizes Get Quote

Product Details

Antibody Target Swi6
Alternate Name Chromatin-associated protein swi6
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide from the middle of the sequence
Accession # Q1ZZU3
Gene ID 375757
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot
Application & Usage Western blot: 1:200
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Swi6 protein of fission yeast is a functional and structural homolog of HP1 (Heterochromatin Protein 1) of animals and is involved in the formation of heterochromatin structure by binding to centromere, telomere and silent mating-type locus. It is also involved in silencing the genes and sister chromatid cohesion by binding to histone H3 methylated at Lys9 and the cohesin subunit Psc3. It is also involved in the repression of the silent mating-type loci MAT2 and MAT3. It may compact MAT2/3 into a heterochromatin-like conformation which represses the transcription of these silent cassettes.


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