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Superoxide Dismutase (SOD-1) Antibody

Catalog #: 3458
SKU-Size Size Price Qty
3458-30T 30 µg
$89.00
3458-100 100 µg
$255.00
More Sizes Get Quote

Product Details

Antibody Target SOD-1
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen Synthetic peptide surrounding amino acid 131 of human SOD
Accession # AAR21563
Gene ID 6647
Appearance Colorless liquid
Concentration 0.2 mg/ml
Formulation 100 µg (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified
Species Reactivity Human, mouse, rat
Application Western blot, Immunoprecipitation, Immunohistochemistry
Application & Usage Western blotting (0.5-4 µg/ml), immunoprecipitation (20 µg/ml) and Immunohistochemistry (20 µg/ml, frozen & paraffin). However, the optimal concentrations should be determined individually.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

SOD (Superoxide Dismutase) is a well characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide, and it also catalyzes prooxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases.


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Jonathan Martínez-Fábregas, Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis. Nat Commun, Dec 2018; 30559339.
Eram Fauzia, et al., (2018) Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism, Frontiers in Pharmacology, Sep.2018, 30298003
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