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Sulindac

A COX-2 inhibitor
Catalog #: B3382
SKU-Size Size Price Qty
B3382-1G 1 g
$65.00
B3382-5G 5 g
$225.00
More Sizes Get Quote

Product Details

Alternate Name 5-fluoro-2-methyl-1Z-[[4-(methylsulfinyl)phenyl]methylene]-1H-indene-3-acetic acid
Appearance Yellow solid
CAS # 38194-50-2
Molecular Formula C₂₀H₁₇FO₃S
Molecular Weight 356.41
Purity ≥98% by HPLC
Solubility >30 mg/ml DMSO
SMILES CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O
InChi InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-
InChi Key MLKXDPUZXIRXEP-MFOYZWKCSA-N
PubChem CID 1548887
MDL Number MFCD00599589
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Sulindac is non-steroidal anti-inflammatory drug (NSAID) and an analgesic that has antiproliferative and apoptotic effects. It inhibits the expression and activity of cyclooxygenase-2 in human colon cancer cells and reduces tumor burden in adenomatous polyposis patients. Also mediates breast cancer inhibition as an immune modulator.


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