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Sulfo-SMCC

A water-soluble heterobifunctional protein crosslinker
Catalog #: 2320
SKU-Size Size Price Qty
2320-set 1 set (10 x 2 mg)
$165.00
2320-50 50 mg
$165.00
2320-100 100 mg
$295.00
2320-1000 1 g
$2,015.00
More Sizes Get Quote

Product Details

Alternate Name 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt
Appearance White to off-white solid
CAS # 92921-24-9
Molecular Formula C₁₆H₁₇N₂NaO₉S
Molecular Weight 436.37
Purity ≥90% by NMR
Solubility H₂O (>10 mg/ml)
SMILES C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
InChi InChI=1S/C16H18N2O9S.Na/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26;/h5-6,9-11H,1-4,7-8H2,(H,24,25,26);/q;+1/p-1
InChi Key VUFNRPJNRFOTGK-UHFFFAOYSA-M
PubChem CID 4618794
MDL Number MFCD00054978
Handling Protect from moisture
Storage Conditions -20 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

KEY FEATURES:• Amine reactive Sulfo-NHS ester that crosslinks efficiently with primary amine-containing molecules• Has a maleimide functional group that can be utilized to react specifically with cysteines or sulfhydryl (-SH) groups• Water-soluble; can be used under physiologic conditions• Has a spacer arm length of 8.3 Å (9 atom)• Unlike other maleimide-activated antibodies, those made with Sulfo-SMCC crosslinkers are often more stable, due to the inductive stabilizing effects of the cyclohexyl ring moeityAPPLICATIONS:• Routinely used to prepare hapten-carrier protein and antibody-enzyme conjugates, such as HRP conjugation. • Wide range of uses for both small molecule reactions and large biomolecule applications.


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