A useful catalyst in the zero-length crosslinking of proteins
Catalog #: 2321 | abID: ab145608

Product Details

abID ab145608
Alternate Name Hydroxy-2,3-dixopyrrolidine-3-sulfonic acid sodium salt; Sulfo-NHS; SNHS; N-Hydroxysulfosuccinimide sodium salt
Appearance White to off-white solid
CAS # 106627-54-7
Molecular Formula C₄H₄NNaO₆S
Molecular Weight 217.13
Purity ≥95% by NMR
Solubility H₂O (~ 2 mg/ml)
SMILES C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]
InChi InChI=1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1
PubChem CID 3520574
MDL Number MFCD00043100
Handling Protect from moisture
Storage Conditions 4 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


KEY FEATURES:• Sulfo-NHS assists in stabilizing the protein-EDC intermediate, thus allowing for a more efficient crosslinking reaction.• Water-soluble; can be used under physiologic conditions• Assists in converting carboxyl groups to sulfo-NHS esters which react with primary aminesAPPLICATIONS:• Increases the efficiency of EDC-mediated coupling reactions• Useful for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticles• Assists in converting carboxyl groups to primary amine-reactive sulfo-NHS esters

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