A water-soluble, dislulfide-reducible, protein biotinylation reagent.
Catalog #: 2323 | abID:

Product Details

Alternate Name Sulfosuccinimidyl-2-(biotinamido)-ethyl-1,3'-dithiopropionate; Biotin disulfide N-Hydroxysulfosuccinimide ester
Appearance White to off-white solid
CAS # 325143-98-4
Molecular Formula C₁₉H₂₇O₉N₄S₄Na
Molecular Weight 606.69
Purity ≥80% by NMR
Solubility H₂O (~ 6 mg/ml)
InChi InChI=1S/C19H30N4O8S4.Na/c24-15(4-2-1-3-13-17-12(11-32-13)21-19(27)22-17)20-7-10-34-33-9-6-16(25)31-23-8-5-14(18(23)26)35(28,29)30;/h12-14,17H,1-11H2,(H,20,24)(H2,21,22,27)(H,28,29,30);/q;+1/p-1
PubChem CID
MDL Number MFCD00078533
Handling Protect from moisture
Storage Conditions 4 ̊C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


KEY FEATURES:• Sulfo-NHS-SS-Biotin is amine-reactive and• Has a long chain spacer arm (24.3 Å) separating the biotin group from the amino-reactive sulfo-NHS ester • Water-soluble; can be used under physiologic conditions• It is possible to cleave the biotin group from the cross-linked target protein under reducing conditions, such as in the presence of BME, DTT or TCEPAPPLICATIONS:• Sulfo-NHS-SS-Biotin is ideal for biotinylating antibody or protein that can then be used for protein purification, detection or immobilization • Sulfo-NHS-Biotin is particularly useful for targeting cell surface proteins due to the membrane-impermeability of this reagent

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