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Sulfatinib

A potent VEGFR inhibitor
Catalog #: B2466
SKU-Size Size Price Qty
B2466-5 5 mg
$95.00
B2466-25 25 mg
$335.00
More Sizes Get Quote

Product Details

Alternate Name HMPL 012; HMPL012; N-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1H-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide
Appearance Crystalline solid
CAS # 1308672-74-3
Molecular Formula C₂₄H₂₈N₆O₃S
Molecular Weight 480.59
Purity ≥98% by HPLC
Solubility >25 mg/ml DMSO
SMILES CC1=CC2=C(N1)C=CC(=C2)OC3=NC(=NC=C3)NC4=CC=CC(=C4)CS(=O)(=O)NCCN(C)C
InChi InChI=1S/C24H28N6O3S/c1-17-13-19-15-21(7-8-22(19)27-17)33-23-9-10-25-24(29-23)28-20-6-4-5-18(14-20) 16-34(31,32)26-11-12-30(2)3/h4-10,13-15,26-27H,11-12,16H2,1-3H3,(H,25,28,29)
InChi Key TTZSNFLLYPYKIL-UHFFFAOYSA-N
PubChem CID 52920501
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Sulfatinib is a potent, orally bioavailable and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC₅₀s of in a range of 1 to 24 nM.


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