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Sulfasalazine

An anti-inflammatory agent and GST inhibitor
Catalog #: B2331

In stock

SKU-Size Size Price Qty
B2331-1 1 g
$75.00
B2331-5 5 g
$195.00
More Sizes Get Quote

Product Details

Alternate Name 2-hydroxy-5-[2-[4-[(2-pyridinylamino)sulfonyl]phenyl]diazenyl]-benzoic acid,NSC-667219,NSC-203730
Appearance Light yellow to light brown solid
CAS # 599-79-1
Molecular Formula C₁₈H₁₄N₄O₅S
Molecular Weight 398.39
Purity ≥98%
Solubility >25 mg/ml (DMSO)
SMILES C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O
InChi InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,20H,(H,19,22)(H,24,25)/b21-13-
InChi Key OQANPHBRHBJGNZ-BKUYFWCQSA-N
PubChem CID 5359476
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Sulfasalazine is an anti-inflammatory agent and GST inhibitor. Sulfasalazine inhibits TNF-α and LPS-induced NF-κB activation in SW620 colon cancer cells. It also inhibits degradation of IκBα and prevents nuclear translocation of NF-κB induced by TNF-α.


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