Product Details
| Alternate Name | Suc-LLVY-AMC; Proteasome Substrate; Calpain Substrate |
|---|---|
| Appearance | Lyophilized solid |
| CAS # | 94367-21-2 |
| Molecular Formula | C₄₀H₅₃N₅O₁₀ |
| Molecular Weight | 763.88 |
| Purity | ≥98% by HPLC |
| Solubility | DMSO (~ 5 mM) |
| SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)CCC(=O)O |
| InChi | InChI=1S/C40H53N5O10/c1-21(2)16-29(42-33(47)14-15-34(48)49)38(52)43-30(17-22(3)4)39(53)45-36(23(5)6)40(54)44-31(19-25-8-11-27(46)12-9-25)37(51)41-26-10-13-28-24(7)18-35(50)55-32(28)20-26/h8-13,18,20-23,29-31,36,46H,14-17,19H2,1-7H3,(H,41,51)(H,42,47)(H,43,52)(H,44,54)(H,45,53)(H,48,49)/t29-,30-,31-,36-/m0/s1 |
| InChi Key | UVFAEQZFLBGVRM-MSMWPWNWSA-N |
| PubChem CID | 10234210 |
| MDL Number | MFCD00080248 |
| Handling | Protect from moisture and light |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
A widely used fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorometrically. λex: 340 - 360 nm; λem: 440 - 460 nm.
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