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Streptokinase Activity Assay Kit (Colorimetric)

to evaluate Streptokinase produced in bulk culture
Catalog #: K2008
$425.00

Product Details

Cat # +Size K2008-100
Size 100 assays
Kit Summary Human Streptokinase is a therapeutic drug and is used as a fibrinolytic agent to treat patients with acute myocardial infarction. Streptokinase (SK) is a plasminogen activator, which works by binding to plasminogen to form a catalytically active streptokinase-plasminogen enzymatic complex (Plg-SK) thereby converting plasminogen to plasmin. In nature, Streptokinase is produced by Group A and Group C Streptococci. SK helps Streptococci in hijacking plasminogen in the human fibrinolytic system thereby dissolving the host fibrin barriers and facilitating bacterial spreading. SK is listed in the World Health Organization (WHO) Model List of essential medicines and is a leading fibrinolytic agent in the treatment of thromboembolic conditions. It is cost-effective and is easy to produce. BioVision’s Steptokinase Activity Assay Kit can be used to evaluate Streptokinase produced in bulk culture and its effect on plasminogen activation in serum. The assay is simple, easy to perform and can be completed in 3 easy steps. The assay can detect as little as 3 mU of Streptokinase Activity in less than 60 min. The overall reaction is as follows: Plasminogen + SK Plg-SK SK + Plasmin Plasmin + SK Substrate Plasmin-SK Substrate Plasmin + pNA (Absorbance 405 nm)
Detection Method Absorbance, OD 405 nm
Species Reactivity Streptokinase
Applications Determination of recombinant Streptokinase activity in bulk preparation for comparison with the in-house bulk-preparation.
Features & Benefits • Easy to perform and can be completed in 3 easy steps
• Can detect as little as 3 mU of Streptokinase Activity in less than 60 min
• Simple
Kit Components Streptokinase
pNA Standard
Plasminogen
SK Assay Buffer
SK Substrate Buffer
SK Substrate
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Human Streptokinase is a therapeutic drug and is used as a fibrinolytic agent to treat patients with acute myocardial infarction. Streptokinase (SK) is a plasminogen activator, which works by binding to plasminogen to form a catalytically active streptokinase-plasminogen enzymatic complex (Plg-SK) thereby converting plasminogen to plasmin. In nature, Streptokinase is produced by Group A and Group C Streptococci. SK helps Streptococci in hijacking plasminogen in the human fibrinolytic system thereby dissolving the host fibrin barriers and facilitating bacterial spreading. SK is listed in the World Health Organization (WHO) Model List of essential medicines and is a leading fibrinolytic agent in the treatment of thromboembolic conditions. It is cost-effective and is easy to produce. BioVision’s Steptokinase Activity Assay Kit can be used to evaluate Streptokinase produced in bulk culture and its effect on plasminogen activation in serum. The assay is simple, easy to perform and can be completed in 3 easy steps. The assay can detect as little as 3 mU of Streptokinase Activity in less than 60 min.


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