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sTNF-RI, human recombinant

Mediates TNF-alpha induced sickness behavior & neurotoxic processes
Catalog #: 4348
SKU-Size Size Price Qty
4348-20 20 μg
4348-100 100 μg
4348-1000 1 mg
More Sizes Get Quote

Product Details

Alternate Name Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, TNF-R1, TNF-RI, TNFR-I, p60, p55, CD120a, TNFRSF1A, TNFAR, TNFR1, FPF, TBP1, TNF-R, p55-R, TNFR55, TNFR60, TNF-R-I, TNF-R55, MGC
Gene Symbol TNR1A
Gene ID 7132
Accession # AAA36756
Source E. coli
Appearance Lyophilized protein
Physical Form Description Sterile filtered and lyophilized in 5 mM Tris pH 8.0
Molecular Weight 18.3 kDa
Purity by SDS-PAGE ≥98%
Purity by ≥98%
Endotoxin Level <0.1 ng/μg
Biological Activity The biological activity of sTNF-RI was determined by its inhibitory effect of the TNF-α mediated cytotoxicity in murine L-929 cells. The ED₅₀ for the effect in the presence of 0.25 ng/ml of recombinant TNF-α, is 0.05 mg/ml.
Reconstitution Instructions Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers or stored at –4°C for 1 week or –20°C for future use.
Handling Centrifuge the vial prior to opening.
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not to be used in humans


Tumor Necrosis Factor receptor type I (TNF-RI) is also referred as p60. The p60 form of the receptor is primarily expressed on epithelial cells. Recombinant Human soluble TNF receptor Type I (sTNF-RI) is a 18.3 kDa protein containing 162 amino acid residues comprising the extra Cellular domain of TNF Receptor Type I.

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