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STING Antagonist, C-178

A STING antagonist
Catalog #: B2396
SKU-Size Size Price Qty
B2396-5 5 mg
$75.00
B2396-25 25 mg
$295.00
More Sizes Get Quote

Product Details

Alternate Name C-178, STING Antagonist, N-3-Dibenzofuranyl-5-nitrofuran-2-carboxamide
Appearance Orange solid
CAS # 329198-87-0
Molecular Formula C₁₇H₁₀N₂O₅
Molecular Weight 322.28
Purity ≥98% by HPLC
Solubility >25 mg/ml in DMSO
SMILES C1=CC=C2C(=C1)C3=C(O2)C=C(C=C3)NC(=O)C4=CC=C(O4)[N+](=O)[O-]
InChi InChI=1S/C17H10N2O5/c20-17(14-7-8-16(24-14)19(21)22)18-10-5-6-12-11-3-1-2-4-13(11)23-15(12)9-10/h1-9H,(H,18,20)
InChi Key URUVDCCYSJEGQQ-UHFFFAOYSA-N
PubChem CID 2866412
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

STING Antagonist C-178 is a potent inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.


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