Product Details
| Alternate Name | PY*LKTK-mts (where Y* = phosphotyrosine) |
|---|---|
| Peptide Sequence | H-Pro-Tyr-(PO₃H₂)-Leu-Lys-Thr-Lys-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro-OH. CF3CO2H |
| Appearance | White lyophilized solid |
| Molecular Formula | C₉₂H₁₅₇N₂₀O₂₄P .C₂HF₃O₂ |
| Molecular Weight | 1958.32 . 114.02 |
| Purity | ≥95% by HPLC |
| Solubility | H₂O |
| Handling | Protect from air and moisture |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Cell-permeable. A peptide-based inhibitor, PY*LKTK-mts (mts = membrane translocating sequence) that selectively inhibits constitutive and ligand-induced activation of Stat3 in vivo. Also suppresses transformation by Src oncoprotein that requires constitutive Stat3 activation.
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