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SR1001

A high affinity synthetic ligand to retinoic acid-related orphan receptors ɑ (RORɑ) and γt
Catalog #: 1902
SKU-Size Size Price Qty
1902-5 5 mg
$100.00
1902-25 25 mg
$405.00
More Sizes Get Quote

Product Details

Alternate Name N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulphamoyl)-4-methylthiazol-2-yl)acetamide
Appearance Cream solid
Molecular Formula C₁₅H₁₃F₆N₃O₄S₂
Molecular Weight 477.4
Purity ≥98% by TLC and NMR
Solubility DMSO (10 mg/ml)
PubChem CID
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Cell-permeable. A high affinity synthetic ligand specific to both retinoic acid-related orphan receptors ɑ (RORɑ) and γt (RORγt). SR1001 inhibits interleukin-17 (TH17) cell differentiation and function as well as suppressing the clinical severity of autoimmune disease in mice.


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