Call 408.493.1800 | Fax 408.493.1801 | Toll Free 800.891.9699 (US Only) | Email: [email protected]

Splitomicin

A HDAC inhibitor
Catalog #: 1610
$130.00

Product Details

Cat # +Size 1610-5
Size 5 mg
Alternate Name 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
Appearance White to off-white solid
CAS # 5690-03-9
Molecular Formula C₁₃H₁₀O₂
Molecular Weight 198.2
Purity ≥98%
Solubility DMSO (100 mg/ml)
SMILES C1CC(=O)OC2=C1C3=CC=CC=C3C=C2
InChi InChI=1S/C13H10O2/c14-13-8-6-11-10-4-2-1-3-9(10)5-7-12(11)15-13/h1-5,7H,6,8H2
InChi Key ISFPDBUKMJDAJH-UHFFFAOYSA-N
PubChem CID 5269
MDL Number MFCD08705254
Handling Protect from air and moisture
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Potent inhibitor of yeast NAD⁺-dependent histone deacetylase Sir2p (IC₅₀ = 60 µM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket.


Why buy BioVision Products?
Innovation
Affordability
Global Presence
Technical Support
BioVision aims to provide our customers innovative tools for accelerating drug discovery and biological research. BioVision offers >8,000 products including the most comprehensive array of assay kits for key targets in Metabolic pathways.
BioVision is committed to providing the highest quality products at a competitive price.
We have a broad network of global distributors who are ready to address your research needs and ensure fast delivery.
Our highly trained Technical Support team provides comprehensive product support and is dedicated to resolving your issues quickly and efficiently.