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A HDAC inhibitor
Catalog #: 1610

Product Details

Cat # +Size 1610-5
Size 5 mg
Alternate Name 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
Appearance White to off-white solid
CAS # 5690-03-9
Molecular Formula C₁₃H₁₀O₂
Molecular Weight 198.2
Purity ≥98%
Solubility DMSO (100 mg/ml)
InChi InChI=1S/C13H10O2/c14-13-8-6-11-10-4-2-1-3-9(10)5-7-12(11)15-13/h1-5,7H,6,8H2
PubChem CID 5269
MDL Number MFCD08705254
Handling Protect from air and moisture
Storage Conditions 4°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.


Potent inhibitor of yeast NAD⁺-dependent histone deacetylase Sir2p (IC₅₀ = 60 µM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket.

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