An USP10 and USP13 inhibitor
Catalog #: 2037 | abID: ab142205

Product Details

abID ab142205
Alternate Name 6-Fluoro-N-(4-fluorobenzyl)quinozaline-4-amine
Appearance White solid
CAS # 1262888-28-7
Molecular Formula C₁₅H₁₁F₂N₃
Molecular Weight 271.26
Purity ≥97% by HPLC
Solubility DMSO (~ 100 mM)
PubChem CID
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A specific and potent autophagy inhibitor in mammalian cells. It promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin specific peptidases, USP10 and USP13, that target the Beclin1 subunit of Vps34 complexes. Spautin-1 blocks the prosurvival autophagy pathway in cancer cells.

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