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Sox-2 Antibody (Clone # 57CT23.3.4)

Monoclonal Antibody to detect Sox-2 in human samples.
Catalog #: 6772
$265.00

Product Details

Cat # +Size 6772-100
Size 100 μl
Antibody Target Sox-2
Alternate Name SOX2; Transcription factor SOX-2
Host Mouse
Antibody Type Monoclonal
Isotype Mouse IgG1
Immunogen SOX2 recombinant protein is used to produce this monoclonal antibody.
Accession # P48431
Gene ID 6657
Appearance Colorless liquid
Formulation This antibody is purified through a protein G column, followed by dialysis against PBS.
Species Reactivity Human.
Application Western blot, IHC, FACS, IF.
Positive Control Western blot: SOX-2 protein, IHC: human lung carcinoma, FACS: NCI-H460 cells, IF: A549 and SY5S cells.
Application & Usage Western blot: ~1:200 – 1:2000, IHC: 1:50 – 1:100, FACS: 1:10 – 1:50, IF: 1:100.
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes clusters at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.


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Mei-Hwa Lee. Cellular reprogramming with multigene activation by the delivery of CRISPR/dCas9 ribonucleoproteins via magnetic peptide-imprinted chitosan nanoparticles. Mater Today Bio. Jan 2021. 33521619.  
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