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Solamargine

An anticancer agent
Catalog #: B1586

In stock

SKU-Size Size Price Qty
B1586-5 5 mg
$125.00
B1586-25 25 mg
$495.00

Product Details

Alternate Name Solasodine-L-rhamnosido-D-glucoside (3b,22a,25R)-Spirosol-5-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(1→2)-O-[6-deoxy-a-L-mannopyranosyl-(1→4)]-b-D-glucopyranoside
Appearance White to of-white solid
CAS # 20311-51-7
Molecular Formula C₄₅H₇₃NO₁₅
Molecular Weight 868.07
Purity ≥95%
Solubility DMSO
SMILES CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)OC9C(C(C(C(O9)C)O)O)O)C)C)C)NC1
InChi InChI=1S/C45H73NO15/c1-19-9-14-45(46-17-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(53)34(51)32(49)22(4)56-41)37(54)38(29(18-47)58-42)59-40-35(52)33(50)31(48)21(3)55-40/h7,19-22,24-42,46-54H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1
InChi Key MBWUSSKCCUMJHO-ZGXDEBHDSA-N
PubChem CID 73611
Handling Protect from air and light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Solamargine is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicinal herb, Solanum nigrum L. (SNL). It has been shown to inhibit growth and induce apoptosis of various cancer cells. Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic mitochondrial death pathway.


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