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Product Details
| Alternate Name | TUDCA 3α,7β-dihydroxy-5β-cholanoyl Taurine 2-[[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic acid, monosodium salt |
|---|---|
| CAS # | 35807-85-3 |
| Molecular Formula | C₂₆H₄₄NO₆S • Na |
| Molecular Weight | 521.69 |
| Purity | ≥98% |
| Solubility | >100 mg/ml DMSO, >100 mg/ml Water |
| SMILES | C[[email protected]](CCC(NCCS([O-])(=O)=O)=O)[[email protected]@]1([H])CC[[email protected]@]2([H])[[email protected]]3([H])[[email protected]@H](O)C[[email protected]]4([H])C[[email protected]](O)CC[[email protected]]4(C)[[email protected]@]3([H])CC[[email protected]@]21C.[Na+] |
| InChi | InChI=1S/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-;/m1./s1 |
| InChi Key | IYPNVUSIMGAJFC-JUWYWQLMSA-M |
| PubChem CID | 46782978 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20ºC |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Tauroursodeoxycholic acid (TUDCA) is a taurine-conjugated form of the secondary bile acid ursodeoxycholic acid. TUDCA is found in small quantities in human bile but at a higher concentration in the bile of black bears. It acts as an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12.
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