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Sodium butyrate

A HDAC inhibitor
Catalog #: 1609
$130.00

Product Details

Cat # +Size 1609-1000
Size 1 g
Alternate Name Butyric acid, Sodium salt, NaB
Appearance White solid
CAS # 156-54-7
Molecular Formula C₄H₇O₂ . Na
Molecular Weight 110.1
Purity ≥99% by HPLC
Solubility H₂O (100 mM)
SMILES CCCC(=O)[O-].[Na+]
InChi InChI=1S/C4H8O2.Na/c1-2-3-4(5)6;/h2-3H2,1H3,(H,5,6);/q;+1/p-1
InChi Key MFBOGIVSZKQAPD-UHFFFAOYSA-M
PubChem CID 5222465
MDL Number MFCD00002816
Handling Protect from air and moisture
Storage Conditions RT
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

A short chain fatty acid shown to be an inhibitor of histone deacetylase (HDAC). Induce apoptosis in colon carcinoma cell lines in a p53-independent pathway. Inhibits c-myc splicing and inteferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Downregulates the activity of serine/threonine protease kinase casein kinase II in HT29 cells.


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