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Smo Agonist, SAG

A Smoothened (Smo) agonist
Catalog #: 1939
SKU-Size Size Price Qty
1939-1 1 mg
1939-5 5 mg
More Sizes Get Quote

Product Details

Alternate Name N-Methyl-N′-(3-pyridinylbenzyl)-N′-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane
Appearance Off-white solid
CAS # 912545-86-9
Molecular Formula C₂₈H₂₈ClN₃OS
Molecular Weight 490.06
Purity ≥98% by NMR
Solubility DMSO (>40 mg/ml)
Handling Protect from light
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Cell-permeable. A Smoothened (Smo) agonist that has shown to induce Hedgehog pathway activation and counteract cyclopamine inhibition of Smo. SAG has been reported to act as an activator at low concentrations, but can inhibit Smo at very high concentrations.

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