Product Details
| Alternate Name | ADENOSYL-ORNITHINE, (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid, Decofuranuronic acid, 6,9-diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-, (5S)-5-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-L-norleucine, D-glycero-alpha-L-talo-Decofuranuronic acid, 6,9-diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-, A 9145, Antibiotic A 9145, Antibiotic 32232RP, RP 32232 |
|---|---|
| Appearance | Solid |
| CAS # | 58944-73-3 |
| Molecular Formula | C₁₅H₂₃N₇O₅ |
| Molecular Weight | 381.39 |
| Purity | ≥95% |
| Solubility | ~20 mg/ml in Water |
| SMILES | C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CC(CCC(C(=O)O)N)N)O)O |
| InChi | InChI=1S/C15H23N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h4-8,10-11,14,23-24H,1-3,16-17H2,(H,25,26)(H2,18,19,20)/t6-,7-,8+,10+,11+,14+/m0/s1 |
| InChi Key | LMXOHSDXUQEUSF-YECHIGJVSA-N |
| PubChem CID | 65482 |
| Handling | Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure. |
| Storage Conditions | -20°C |
| Shipping Conditions | RT |
| USAGE | For Research Use Only! Not For Use in Humans. |
Details
Sinefungin is a natural nucleoside and a structural analog of S-adenosylmethionine (SAM). It inhibits SAM-dependent nucleic acid methyltransferases and exhibits antifungal, antiviral, and antiprotozoal properties. It is a non-selective inhibitor of SET domain-containing methyltransferases and is a pan-protein arginine N-methyltransferases (PRMT) inhibitor.
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