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Sinefungin

An inhibitor of methyltransferases
Catalog #: B2824
SKU-Size Size Price Qty
B2824-500 500 µg
$95.00
B2824-1000 1000 μg
$165.00
More Sizes Get Quote

Product Details

Alternate Name ADENOSYL-ORNITHINE, (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid, Decofuranuronic acid, 6,9-diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-, (5S)-5-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-L-norleucine, D-glycero-alpha-L-talo-Decofuranuronic acid, 6,9-diamino-1-(6-amino-9H-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-, A 9145, Antibiotic A 9145, Antibiotic 32232RP, RP 32232
Appearance Solid
CAS # 58944-73-3
Molecular Formula C₁₅H₂₃N₇O₅
Molecular Weight 381.39
Purity ≥95%
Solubility ~20 mg/ml in Water
SMILES C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CC(CCC(C(=O)O)N)N)O)O
InChi InChI=1S/C15H23N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h4-8,10-11,14,23-24H,1-3,16-17H2,(H,25,26)(H2,18,19,20)/t6-,7-,8+,10+,11+,14+/m0/s1
InChi Key LMXOHSDXUQEUSF-YECHIGJVSA-N
PubChem CID 65482
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20°C
Shipping Conditions RT
USAGE For Research Use Only! Not For Use in Humans.

Details

Sinefungin is a natural nucleoside and a structural analog of S-adenosylmethionine (SAM). It inhibits SAM-dependent nucleic acid methyltransferases and exhibits antifungal, antiviral, and antiprotozoal properties. It is a non-selective inhibitor of SET domain-containing methyltransferases and is a pan-protein arginine N-methyltransferases (PRMT) inhibitor.


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