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A eukaryotic translation initiation factor 4A (eIF4A) inhibitor
Catalog #: B2417

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SKU-Size Size Price Qty
B2417-100 100 μg
B2417-500 500 μg
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Product Details

Alternate Name (-)-silvestrol, methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1R)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy] -1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate
Appearance Solid
CAS # 697235-38-4
Molecular Formula C₃₄H₃₈O₁₃
Molecular Weight 654.66
Purity ≥95%
Solubility >5 mg/ml in DMSO
InChi InChI=1S/C34H38O13/c1-40-20-12-10-19(11-13-20)34-27(18-8-6-5-7-9-18)26(30(38)42-3)29(37)33(34,39)28-23(41-2)14-21 (15-24(28)47-34)45-32-31(43-4)44-17-25(46-32)22(36)16-35/h5-15,22,25-27,29,31-32,35-37,39H,16-17H2,1-4H3/t22-,25-, 26-,27-,29-,31-,32-,33+,34+/m1/s1
PubChem CID 11787114
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.


Silvestrol is a natural product isolated from the fruits and twigs of Aglaia foveolata. Acts as a eukaryotic translation initiation factor 4A (eIF4A) inhibitor. Also displays broad-spectrum antiviral activity in infected primary cells by inhibiting eIF4A-dependent viral mRNA translation.

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