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Anti-SHH Antibody

Polyclonal Antibody to detect SHH in Human, Mouse samples
Catalog #: A1017
$265.00

Product Details

Cat # +Size A1017-100
Size 100 µg
Antibody Target SHH
Alternate Name Sonic hedgehog protein, HHG-1, SHH
Host Rabbit
Antibody Type Polyclonal
Isotype Rabbit IgG
Immunogen mouse recombinant SHH (Cat. No. 4020)
Accession # Q62226
Gene ID 20423
Appearance Colorless liquid
Concentration 0.5 mg/ml
Formulation 100 µg (0.5 mg/ml) of antibody in PBS pH 7.2, 0.01 % BSA, 0.03 % ProClin®, and 50 % glycerol.
Purification Affinity purified rabbit IgG
Species Reactivity Human, Mouse
Application Western blot
Positive Control Western blot
Application & Usage Western blot: 1-4 µg/ml
Handling The antibody solution should be gently mixed before use.
Storage Conditions -20 °C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO.


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