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SH-5

An Akt inhibitor
Catalog #: 1818
$235.00

Product Details

Cat # +Size 1818-500
Size 500 µg
Alternate Name D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate
Appearance White to off-white solid
CAS # 701976-54-7
Molecular Formula C₂₉H₅₉O₁₀P
Molecular Weight 598.75
Purity ≥98%
Solubility DMSO (10 mg/ml)
SMILES CCCCCCCCCCCCCCCCCCOCC(COP(=O)(O)OC1C(CC(C(C1O)O)O)OC)OC
InChi InChI=1S/C29H59O10P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-37-22-24(35-2)23-38-40(33,34)39-29-26(36-3)21-25(30)27(31)28(29)32/h24-32H,4-23H2,1-3H3,(H,33,34)/t24-,25?,26?,27?,28?,29?/m1/s1
InChi Key NRLLDDPUQZQEDV-UXPKSZKYSA-N
PubChem CID 16760282
Handling Protect from air and moisture
Storage Conditions -20°C
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

Details

A cell-permeable inhibitor of Akt activation without affecting the activation of the upstream kinase PDK1 or other kinases downstream of Ras such as MAPK. Induces apoptosis and kills a variety of cancer cell lines containing high levels of active Akt.


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